Gene Details:
- Gene ID:
- Gene Symbol: NbRAF2
- Gene Name: Rubisco assembly factor 2
- Genome:
- Species: Nicotiana benthamiana
Functional Descriptions:
- Rubisco assembly factor 2 (NbRAF2), which localizes in the nucleus, cell periphery, chloroplasts, and stromules.
- Tobacco rattle virus-based virus-induced gene silencing of NbRAF2 promoted BrYV-A infection in N. benthamiana, and the overexpression of nuclear NbRAF2 inhibited BrYV-A accumulation.
- Potato leafroll virus P0PL also interacted with NbRAF2 and decreased its nuclear accumulation, indicating that NbRAF2 may be a common target of poleroviruses.
- These results suggest that nuclear NbRAF2 possesses antiviral activity against BrYV-A infection, and that BrYV-A P0BrA interacts with NbRAF2 and alters its localization pattern to facilitate virus infection.
Function-related keywords:
Literature:
- Brassica yellows virus P0 protein impairs the antiviral activity of NbRAF2 in Nicotiana benthamiana. DOI: 10.1093/jxb/ery131 ; PMID: 29659986
Related News:
Gene Resources:
- NCBI ID: MG560271.1
- UniProt accessions:
Orthologs:
Sequences:
- CDS Sequence:
- Protein Sequence: