Gene Details:

  • Gene ID:
  • Gene Symbol: NbBAG5
  • Gene Name: B-cell lymphoma2-associated athanogenes5
  • Genome:
  • Species: Nicotiana benthamiana

Functional Descriptions:

  • Through overexpression and down-regulation of NbBAG5, results showed that NbBAG5 could negatively regulate ToCV infection.
  • NbBAG5 inhibited the expression of mitophagy-related genes and the number of autophagosomes, thereby regulating viral infection by affecting mitophagy.
  • This study demonstrated that ToCV p22 affects autophagy by interacting with NbBAG5, established the association between viral infection, BAG proteins family, and the autophagy pathway, and explained the molecular mechanism by which ToCV p22 interacts with NbBAG5 to inhibit autophagy to regulate viral infection.

Literature:

Gene Resources:

Orthologs:

Sequences:

  • CDS Sequence:
  • Protein Sequence: