Gene Details:
- Gene ID: MtrunA17_Chr3g0137174
- Gene Symbol: MtEFD2
- Gene Name: ETHYLENE RESPONSE FACTOR REQUIRED FOR NODULE DIFFERENTIATION 2
- Genome: Mt5.0 genome browser (https://medicago.toulouse.inra.fr/MtrunA17r5.0-ANR/)
- Species: Medicago truncatula
Functional Descriptions:
- MtEFD and MtEFD2: Two transcription factors with distinct neofunctionalization in symbiotic nodule development.
- A domain swap experiment showed that MtEFD2 differs from MtEFD by its C-terminal fraction outside the DNA binding domain. Furthermore, clustered regularly interspaced short palindromic repeats-CRISPR associated protein 9 (CRISPR-Cas9) mutagenesis of MtEFD2 led to a reduction in the number of nodules formed in Mtefd-1, with downregulation of a set of genes, including notably NUCLEAR FACTOR-YA1 (MtNF-YA1) and MtNF-YB16, which are essential for nodule meristem establishment.
- Conclude that nitrogen-fixing symbiosis recruited two proteins originally expressed in roots, MtEFD and MtEFD2, with distinct functions and neofunctionalization processes for each of them.
- MtEFD and MtEFD2, which exhibit distinct but overlapping expression profiles, could both be involved in the control of nodulation.
Function-related keywords:
- nitrogen , transcription-factor , development , meristem , symbiosis , nodule , nodulation , protein
Literature:
- MtEFD and MtEFD2: Two transcription factors with distinct neofunctionalization in symbiotic nodule development. DOI: 10.1093/plphys/kiac177 ; PMID: 35471237
Related News:
Gene Resources:
Orthologs:
Sequences:
- CDS Sequence:
- Protein Sequence: