Gene Details:

• Gene ID: Medtr7g029760
• Gene Symbol: NCR169
• Gene Name: nodule-specific cysteine-rich 169
• Genome:
• Species: Medicago truncatula

Functional Descriptions:

• Widely conserved AHL transcription factors are essential for NCR gene (NCR169) expression and nodule development in Medicago.
• Introduction of the Medicago truncatula NCR169 gene under its own promoter into soybean roots resulted in its nodule-specific expression, leading to bacteroid changes associated with terminal differentiation.
• Whereas mutation of NCR169 arrested bacteroid development at a late stage, the absence of MtAHL1 or MtAHL2 completely blocked bacteroid differentiation indicating that they also regulate other NCR genes required for the development of nitrogen-fixing nodules.
• NCR169-induced increase in the size of soybean bacteroids is in line with the role of NCR169 in M. truncatula, confirming that the NCR169 peptide is expressed in and can function in soybean nodules.
• NCR169 was induced in the cell layers in which bacteroid elongation was most pronounced, and high expression persisted throughout the nitrogen-fixing nodule zone.
• Our results provide evidence for an essential role of NCR169 in the differentiation and persistence of nitrogen fixing bacteroids in M. truncatula.

Function-related keywords:

• nitrogen ,  development ,  cell-elongation ,  nodule

Literature:

• Loss of the nodule-specific cysteine rich peptide, NCR169, abolishes symbiotic nitrogen fixation in the Medicago truncatula dnf7 mutant.   DOI:  10.1073/pnas.1500777112 ;  PMID:  26401023
• Widely conserved AHL transcription factors are essential for NCR gene expression and nodule development in Medicago.   DOI:  10.1038/s41477-022-01326-4 ;  PMID:  36624259

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Orthologs:

Sequences:

• CDS Sequence:
• Protein Sequence: