Gene Details:

  • Gene ID:
  • Gene Symbol: Cm-eIF4E
  • Gene Name: eukaryotic translation initiation factor 4E
  • Genome:
  • Species: Cucumis melo

Functional Descriptions:

  • Melon RNA interference (RNAi) lines silenced for Cm-eIF4E show broad virus resistance.
  • Cm-eIF4E knockdown melon plants were generated by the transformation of explants with a construct that was designed to induce the silencing of this gene, and the plants from T2 generations were genetically and phenotypically characterized.
  • In transformed plants, Cm-eIF4E was specifically silenced, as identified by the decreased accumulation of Cm-eIF4E mRNA and the appearance of small interfering RNAs derived from the transgene, whereas the Cm-eIF(iso)4E mRNA levels remained unaffected.
  • Cm-eIF4E controls melon susceptibility to these four viruses. Therefore, Cm-eIF4E is an efficient target for the identification of new resistance alleles able to confer broad-spectrum virus resistance in melon.

Literature:

Gene Resources:

Orthologs:

Sequences:

  • CDS Sequence:
  • Protein Sequence: